NUS Researchers Combine 3D Bioprinting with AI to Personalize Gum Tissue Grafts
Researchers at the National University of Singapore (NUS) have developed a groundbreaking method that merges 3D bioprinting with artificial intelligence (AI) to create customized gum tissue grafts. This innovation could offer a less invasive alternative to traditional grafting procedures, which often require harvesting tissue from the patient’s own mouth — a process that can be both painful and limited by tissue availability.
Using AI, the team was able to optimize the bioprinting process, cutting down on the number of experimental trials typically needed. This advancement not only speeds up production but also improves the precision and effectiveness of the personalized grafts.
The newly developed bioprinted grafts showed over 90% cell viability and closely mimicked the structure and function of natural gum tissue. This holds exciting potential for improving dental procedures, especially in cases of gum recession or periodontal disease.
Looking ahead, the researchers plan to conduct in vivo studies to evaluate how these grafts perform in real-world clinical settings. They are also exploring the addition of vascular networks within the grafts, which could expand their use beyond dentistry into broader regenerative medicine fields.
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